What is Regulation Of Bile Secretion? Its Group And Details About Process

Regulation Of Bile Secretion:

Bile secretion is a continuous process though the amount is less during fasting. It starts increasing after meals and continues for three hours. Secretion of bile from liver and release of bile from the gallbladder are influenced by some chemical factors, which are categorized into three groups:

  • Choleretics
  • Cholagogue
  • Hydrocholeretic Agents

1- Choleretics:

Substances which increase the secretion of bile from liver are known as choleretics. Effective choleretic agents are:

  • Acetylcholine
  • Secretin
  • Cholecystokinin
  • Acid Chyme in Intestine
  • Bile Salts

2- Cholagogues:

Cholagogue is an agent which increases the release of bile into the intestine by contracting gallbladder. Common cholagogues are:

  • Bile Salts
  • Calcium
  • Fatty Acids
  • Amino Acids
  • Inorganic Acids

All these substances stimulate the secretion of cholecystokinin, which in turn causes contraction of gallbladder and now of bile into intestine.

3- Hydrocholeretic Agents:

Hydrocholeretic agent is a substance which causes the secretion of bile from liver, with large amount of water and less amount of  solids. Hydrochloric acid is a hydrocholeretic agent.

Leave a Comment

Scroll to Top